Blend BPC-157 2mg with Thymosin Beta 4 (TB500) 2mg

This blend combines two synthetic peptides, BPC-157 and Thymosin Beta 4, formulated for in vitro laboratory research. These peptides are strictly intended for research purposes only and are not approved for human consumption.

In Vitro Cell Signaling Research

In vitro studies using cultured cell models found that BPC-157 promotes cell proliferation, migration, and angiogenesis-related signaling.¹ These cell-based findings are studied separately from any whole-organism research on the same compound and do not by themselves establish an effect in a living system.

Human Tissue Distribution Research

Immunolocalization studies using human autoptic tissue samples, including tongue, oesophagus, stomach, ileum, colon, liver, and pancreas, examined the distribution of Thymosin Beta 4 across fetal and adult human gastrointestinal tissue.

These studies found distinct differences in Thymosin Beta 4 reactivity between fetal and adult tissue in several organs, contributing to basic research on this peptide's tissue distribution across human development.²

BPC-157 Structural Mechanism

BPC-157 has been studied in laboratory settings for its association with several signaling markers, including nitric oxide signaling markers, cell migration and proliferation markers, and growth factor-related signaling in cell-based systems.

Thymosin Beta 4 Mechanism Research

Thymosin Beta 4 binds to actin, a protein involved in cellular movement, and is studied for its role in the migration and differentiation of stem and progenitor cells in cell-based laboratory models.³

Analytical Verification for Blended Products

For a two-component blend combining a 15-residue peptide with a considerably larger 43-residue peptide, analytical verification is understood to require confirmation of both the individual identity and purity of each component and the ratio between them.

Researchers reviewing documentation for this blend are encouraged to look for HPLC or mass spectrometry data resolving BPC-157 and TB-500 as separate peaks, given the substantial size difference between the two molecules.

Storage and Handling in the Laboratory Setting

BPC-157's proline-rich backbone and TB-500's single methionine residue give the two peptides different degradation sensitivities, the latter being more susceptible to oxidation.

As with the individual peptides, the lyophilized blend is best kept under sub-zero freezer conditions to preserve both components' integrity prior to use.

Important Notice

This peptide blend is provided strictly for in vitro laboratory research and is not suitable for clinical or personal use. Application or ingestion outside of controlled research settings is prohibited, and this product has not been evaluated for safety or efficacy in humans.

Product Information

The blend is supplied as a white lyophilized powder, with each vial containing a total of 4 mg (2 mg of each peptide).

References

1. Huang T et al. Body protective compound-157 promotes proliferation, migration, and angiogenesis in vitro. Drug Des Devel Ther. 2015;9:2485-99.
2. Nemolato S, Cabras T, Cau F, et al. Different Thymosin Beta 4 Immunoreactivity in Foetal and Adult Gastrointestinal Tract. PLoS One. 2010;5(2):e9111.
3. Goldstein AL, Hannappel E, Sosne G, Kleinman HK. Thymosin β4: a multifunctional regenerative peptide. Expert Opin Biol Ther. 2012;12(1):37-51.